Table 1 Characteristics of included dialysis patients and healthy individuals as well as age-matched cohort for DVA.
From: Endothelial dysfunction in retinal vessels of hemodialysis patients compared to healthy controls
Whole cohorts | p-value | Age-matched cohorts for DVA | p-value | |||
|---|---|---|---|---|---|---|
Healthy | Hemodialysis | Healthy | Hemodialysis | |||
n | 192 | 214 | – | 169 | 169 | – |
Age, years, mean ± SD | 65.6 ± 12.5 | 62.6 ± 15.0 | 0.030 | 65.4 ± 12.7 | 65.4 ± 13.1 | 0.996 |
BMI, kg/m2, mean ± SD | 24.4 ± 3.6 | 26.1 ± 5.5 | < 0.001 | 24.5 ± 3.6 | 26.4 ± 5.4 | < 0.001 |
Gender, male in % | 41.7% | 68.2% | < 0.001 | 40.2% | 67.5% | < 0.001 |
Systolic blood pressure, mmHg, mean ± SD | 132 ± 15 | 134 ± 22 | 0.252 | 132 ± 16 | 135 ± 22 | 0.219 |
Diastolic blood pressure, mmHg, mean ± SD | 84 ± 10 | 74 ± 14 | < 0.001 | 84 ± 10 | 74 ± 15 | < 0.001 |
Mean blood pressure, mmHg, mean ± SD | 105 ± 11 | 94 ± 15 | < 0.001 | 106 ± 11 | 94 ± 15 | < 0.001 |
eGFR (mean ± SD; CKD-EPI 2009; ml/min/1.73 m2) | 76 ± 16 | – | – | 77 ± 15 | – | – |
Vascular disease* | 0% | 47.7% | – | 0% | 53.8% | – |
Diabetes mellitus | 0% | 30.8% | – | 0% | 35.5% | – |
Dialysis vintage in months, median [IQR] | – | 48.5 [24.0–79.0] | – | – | 42.0 [21.0–76.0] | – |
Arterial hypertension in % | 18.8% | 94.4% | < 0.001 | 20.7% | 94.5% | < 0.001 |
Hyperlipidemia in % | 17.2% | 57.9% | < 0.001 | 17.8% | 64.5% | < 0.001 |
Nicotine abuse in % | 20.3% | 23.2% | 0.494 | 20.7% | 21.4% | 0.881 |
Calcium channel blocker in medication in % | – | 35.0% | – | – | 36.1% | – |
Vasodilator in medication in % | – | 13.6% | – | – | 14.2% | – |
hsCRP, mg/dl, median [IQR] | 0.13 [0.06–0.26] | 0.36 [0.18–0.81] | < 0.001 | 0.13 [0.06–0.26] | 0.39 [0.19–0.92] | < 0.001 |
