Table 2 Characteristic on the starting medication day.

From: A randomized single-blind non-inferiority trial of delayed start with drospirenone-only and ethinyl estradiol-gestodene pills for ovulation inhibition

On the starting medication day

EE/GS

n = 18

DRSP

n = 18

p-valuea

Cycle day at starting medication, n (%)

0.319

 Day 7

6 (35.29)

5 (29.41)

 

 Day 8

5 (29.41)

9 (52.94)

 

 Day 9

6 (35.29)

3 (17.65)

 

Largest follicle diameter

 Mean ± SD

10.75 ± 3.80

9.76 ± 2.03

0.351

 Median (IQR)

11.70 (8.40–11.80)

10.40 (8.40–10.80)

Estradiol (pg/mL)

 Mean ± SD

112.62 ± 94.54

68.34 ± 33.91

 Median (IQR)

66.54 (37.89, 139.19)

69.87 (42.89, 76.24)

0.502

Progesterone (ng/dL)

 Mean ± SD

0.24 ± 0.17

0.39 ± 0.83

 Median (IQR)

0.19 (0.17, 0.30)

0.13 (0.10, 0.30)

0.407

LH (IU/L)

 Mean ± SD

7.45 ± 4.83

6.52 ± 1.98

 Median (IQR)

5.55 (4.34–8.20)

6.71 (4.76–7.50)

0.945

Cervical mucus (modified WHO score)

 Mean ± SD

5.35 ± 2.00

4.41 ± 1.42

0.123

 Median (IQR)

5 (4–6)

4 (4–5)

Hoogland and Skouby Score at starting medication day, n (%)

0.785

 No activity

8 (47.06)

9 (52.94)

 

 Potential activity

6 (35.29)

7 (41.18)

 

 Non-active FLS

 

 Active FLS

3 (17.65)

1 (5.88)

 

 LUF

 

 Ovulation

 
  1. EE/GS ethinyl estradiol 0.02 mg plus gestodene 0.075 mg, DRSP 4 mg drospirenone, SD standard deviation, IQR interquartile range, FLS follicle like structure, LUF luteinized unruptured follicle.
  2. aStudent t-test, Wilcoxon rank-sum test, Chi-square or fisher's exact tests as appropriate.