Figure 4

Enrichment analysis of KEGG functional pathways. (A) Top 20 functional pathways for metabolite enrichment. From left to right, the number of metabolites in the column was ranked from high to low. The higher the column, the more metabolites are involved in this pathway among the identified metabolites. (B–D) The top 20 pathways of the significance of the up-regulated and down-regulated DEMs on KEGG. The X-axis represented the rich factor, and the Y-axis represented the pathway's name. The bubble size represents the number of DEMs involved. The bubbles color indicates the enrichment degree of the path. Shanghai Majorbio Bio-pharm Technology platform provides all KEGG materials, and the copyright license for image use is obtained.