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Figure 1

From: Boswellia carterii n-hexane extract suppresses breast cancer growth via induction of ferroptosis by downregulated GPX4 and upregulated transferrin

Figure 1

BCHE hindered human breast cancer MCF-7 and MDA-MB-231 cells proliferation. (a) BCHE was added to MCF-7 and MDA-MB-231 cells for 24, 48, and 72 h, and a MTT assay was then conducted to analyze cell viability. (b) These BC cells were subjected to BCHE (20 and 40 µg/mL) treatment for 12 days, followed by colony formation determination. The left and right panels show the typical imaging and quantitative findings, respectively. *P < 0.05, **P < 0.01, ***P < 0.001. (c) MCF-7 and MDA-MB-231 cells were exposed to 48 h of BCHE treatment, followed by EdU and Hoechst 33342 staining. EdU-labeled cells were detected as green fluorescence (488 nm), while the nuclei were stained with Hoechst 33342. The left and right panels show representative images (200 ×) and percentages of EdU-positive cells, respectively.

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