Table 3 ANOVA for spray–drying operating factors’ impact on the response variables for SDM.

Model

14

0.25*

< 0.0001

0.12*

0.0001

1.00*

0.0009

Linear effects

IAT

1

0.12*

0.88

0.004^N.S

0.61

0.24*

0.25

WM

1

0.004^N.S

0.59

0.0006^N.S

0.84

0.35*

0.17

PS

1

0.01^N.S

0.42

0.0002^N.S

0.90

0.51*

0.10

NS

1

4.004**

0.61

0.0002^N.S

0.92

0.08^N.S

0.11

Interaction effects

IAT × WM

1

0.12*

0.48

0.11*

0.59

0.17*

0.33

IAT × PS

1

0.001^N.S

0.75

0.0005^N.S

0.85

0.05^N.S

0.17

IAT × NS

1

0.01^N.S

0.39

0.0008^N.S

0.82

0.24*

0.25

WM × PS

1

0.004^N.S

0.58

0.0003^N.S

0.89

0.35*

0.17

WM × NS

1

0.002^N.S

0.69

0.0002^N.S

0.92

0.08^N.S

0.48

PS × NS

1

1.21*

0.53

2.23**

0.95

0.42*

0.14

Quadratic effects

IAT²

1

0.09^N.S

0.03

0.12*

0.69

0.14*

0.38

WM²

1

0.003^N.S

0.64

0.001^N.S

0.74

0.05^N.S

0.59

PS²

1

0.01^N.S

0.38

0.0005^N.S

0.86

0.52*

0.10

NS²

1

1.02*

0.21

0.003^N.S

0.65

0.49*

0.11

Residual

15

10.01**

–

0.01^N.S

–

2.06*

–

Lack of fit

10

16.02**

0.24

0.02^N.S

0.01

1.09*

0.21

Pure error

5

0.74^N.S

–

0.002^N.S

–

0.002^N.S

–

Cor total

29

–

–

–

–

–

–