Figure 2 | Scientific Reports

Figure 2

From: miR-124-3p downregulates EGR1 to suppress ischemia-hypoxia reperfusion injury in human iPS cell-derived cardiomyocytes

Figure 2

The suppression of apoptosis mediated by IH/R in hiPSC-CMs is achieved by downregulating EGR1 using siRNA. (A,B) Immunofluorescence staining for EGR1 (red), cTnT (green) and DAPI (blue) (n = 8). Scale bars 100 μm. ***P < 0.001, *P < 0.05. (C,D) Immunofluorescence staining for cleaved Caspase-3 (red), cTnT (green) and DAPI (blue) (n = 8). Scale bars 100 μm. ****P < 0.0001, ****P < 0.0001.

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