Table 2 Patient characteristics.
From: Cell free DNA in patients with pancreatic adenocarcinoma: clinicopathologic correlations
Detected (n = 25) | Not detected (n = 56) | p-value | ||
|---|---|---|---|---|
Age | Mean (SD) | 68.8 (9.0) | 66.1 (9.9) | 0.242 |
Sex | F | 7 (28.0) | 24 (42.9) | 0.306 |
M | 18 (72.0) | 32 (57.1) | ||
Time_to_death, months | Median (IQR) | 10.5 (5.5 to 23.0) | 18.0 (10.0 to 36.0) | 0.028 |
Stage | IA | 1 (4.0) | 3 (5.5) | 0.111 |
IB | 4 (16.0) | 2 (3.6) | ||
IIA | 4 (16.0) | 4 (7.3) | ||
IIB | 8 (32.0) | 32 (58.2) | ||
IV | 8 (32.0) | 14 (25.5) | ||
Tumor_grade* | G1 | 4 (21.1) | 19 (45.2) | < 0.001 |
G2 | 4 (21.1) | 19 (45.2) | ||
G3 | 11 (57.9) | 4 (9.5) | ||
Tumor size, mm** | 40.2 (17.4) | 28.8 (10.4) | 0.028 | |
Total_cfDNA_ng | Median (IQR) | 42.5 (31.0 to 89.3) | 46.2 (31.7 to 80.3) | 0.842 |
cfDNA_conc_ng_ml | Median (IQR) | 8.5 (5.6 to 14.9) | 7.7 (5.3 to 13.4) | 0.85 |
cfDNA_input_ng | Mean (SD) | 36.8 (12.4) | 38.0 (12.0) | 0.676 |
Median_Depth of Coverage | Mean (SD) | 50,703.2 (17,345.1) | 49,590.3 (16,633.5) | 0.784 |
