Figure 10
From: Exposure to Gulf war illness-related chemicals exacerbates alcohol-induced liver damage in rodents
PLX3397-mediated depletion of liver macrophages reversed the proinflammatory response to GW-chemicals and EtOH. The proinflammatory cytokines IL-1β (A), IL-6 (B), CCL2 (C) and TNFα (D) were assessed using ELISA in liver samples from Naïve and GWI mice treated with EtOH, PLX or PLX and EtOH vs Naïve and GWI controls. N = 4, p < 0.05. #, vs Naïve controls; $, vs GWI; @, vs GWI + EtOH.
