Figure 3
From: Exposure to Gulf war illness-related chemicals exacerbates alcohol-induced liver damage in rodents
Exposure of mice to GWI-related chemicals resulted in chronic low-grade hepatic inflammation. (A) IHC images of Clec4f. marker of Kupffer cells. (B) Quantification of CLEC4f. of Kupffer cells as percent-stained area. (C) IHC of CD11b marker of infiltrated monocyte-derived macrophages, in liver sections of Naïve and GWI-mice. (D) Image analysis results for CD11b as percent-stained area, by IHC. (E) RT-qPCR for Clec4f. and CD11b in livers of Naïve and GWI mice. (F) RT-qPCR results of proinflammatory genes IL1β, IL6, CCL2 and TNFα in livers of Naïve and GWI mice. N = 4, p < 0.05. #, GWI vs Naïve mice. Scale bar, 25 µm.
