Figure 2

DEPs found in HFpEF vs. Stage A/Healthy. On the left side of the figure we plotted the single-protein associations (adjusted for age and sex) with HFpEF compared to Stage A/Healthy (reference group), resulting from the multinominal regression analysis. The HF group was used as the dependent variable and the protein level as independent variable. All 52 that showed statistically significant associations after adjustment for multiple testing are presented. X-axis is on the log2 scale. The right side of the figure presents a full overview of the comparison of HFpEF with Stage A/Healthy (reference group), resulting from the multinominal regression analysis, including the 52 proteins that showed statistically significant associations, with the top 15 labelled. The y-axis shows the – log 10 adjusted p-value, and the x-axis shows the (natural) log odds ratio.