Table 1 Baseline characteristics.

Age

64 (10)

58 (8)

65 (9)*^†

71 (8)*

68 (10)*

Sex

 Female

403 (55%)

126 (64%)

218 (67%)

31 (69%)

28 (16%)^†

 Male

336 (45%)

72 (36%)

108 (33%)

14 (31%)

142 (84%)^†

BMI

27.2 (4.3)

26.5 (3.8)

27.2 (4.4)^†

29.3 (5.9)*

27.5 (3.9)*

LVEF

61 (17)

68 (8)

67 (7)

66 (8)

28 (9)*^†

eGFR

79 (25)

86 (22)

82 (26)*^†

73 (24)*

63 (21)*^†

DM

99 (13%)

7 (3.5%)

28 (8.6%)*^†

10 (22%)*

54 (32%)*^†

Hypertension

415 (56%)

87 (44%)

210 (64%)*

31 (69%)*

87 (51%)*^†

Dyslipidaemia

131 (18%)

8 (4%)

24 (7.4%)^†

7 (16%)*

92 (54%)*^†

AF

68 (9.2%)

2 (1%)

7 (2.1%)

2 (4.4%)*

57 (34%)*^†

ARB

236 (32%)

12 (6.1%)

50 (15%)*

9 (20%)*

165 (97%)*^†

Diuretics

246 (33%)

21 (11%)

62 (19%)*

14 (31%)*

149 (88%)*^†

Beta-blockers

237 (32%)

18 (9.1%)

53 (16%)*

14 (31%)*

152 (90%)*^†

MRA

124 (17%)

2 (1%)

3 (0.9%)

0 (0%)

119 (70%)*^†

CCB

220 (30%)

15 (7.6%)

35 (11%)

6 (13%)

164 (97%)*^†

Anticoagulants

161 (22%)

5 (2.5%)

15 (4.6%)

7 (16%)*

134 (79%)*^†

Statins

276 (37%)

24 (12%)

89 (27%)*

18 (40%)*

145 (80%)*^†