Table 1 Sociodemographic, genetic ancestry, anthropometric, and clinical characterization of SABE cohort.
From: Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly
Variables | All individuals | Normal weight | Excessive weight | p-value |
|---|---|---|---|---|
N | 1024 | 280 (27.34%) | 744 (72.65%) | – |
Male/female (%) | 365 (35.71%)/657(64.28%) | 115 (41.21%)/164(58.78%) | 250 (33.64%)/493(66.35%) | 0.024 |
Age (years) | 71.31 (59–99) | 74.36 (60–99) | 68.97 (59–98) | < 0.001 |
Ancestry frequencies | ||||
European | 72.53% | 72.08% | 72.69% | 0.79 |
African | 17.89% | 16.13% | 18.55% | 0.04 |
Asian | 2.80% | 5.26% | 1.88% | 0.22 |
Native American | 6.75% | 6.49% | 6.85% | 0.82 |
BMI (kg/m2) | 27.45 (15.13–53.61) | 22.83 (15.13–25) | 29.2 (25.01–53.61) | < 0.001 |
WC (cm) | 94 (62–142) | 82 (64–99) | 98 (62–142) | < 0.001 |
Hypertension (%) | 702 (68.55%) | 167 (59.64%) | 535 (71.9%) | < 0.001 |
SBP (mmHg) | 138 (88–250) | 135 (88–242) | 138.5 (91–250) | 0.13 |
DBP (mmHg) | 79 (49–125) | 76 (50–117) | 80 (49–125) | < 0.001 |
HDL (mg/dl) | 48 (19–133) | 52 (20–124) | 46 (19–133) | < 0.001 |
LDL (mg/dl) | 126 (28–299) | 126 (41–226) | 125 (28–299) | 0.89 |
TC (mg/dl) | 204 (86–388) | 204 (89–321) | 204 (86–388) | 0.94 |
TG (mg/dl) | 115 (25–1283) | 101 (25–436) | 121.5 (34–1283) | < 0.001 |
T2D (%) | 259 (25.29%) | 53 (18.92%) | 206 (27.68%) | 0.004 |
FPG (mg/dl) | 88 (80–102) | 85 (78–95) | 90 (82–105.8) | < 0.001 |
Hb1Ac (%) | 5.8 (4.8–13.7) | 5.7 (4.9–13.6) | 5.8 (4.8–13.7) | < 0.001 |
hsCRP (mg/l) | 2.34 (0.14–141) | 1.43 (0.14–61.5) | 2.83 (0.14–141) | < 0.001 |
Ex/current smoker | 375 (36.62%)/121 (11.81%) | 110 (39.28%)/52 (18.57%) | 265 (35.61%)/69 (9.27%) | < 0.001 |
