Figure 9
From: AI driven analysis of MRI to measure health and disease progression in FSHD
(A) Distribution of (top) clinical STIR grading (from 0 to 4), (middle) STIR content (utilizing the proposed method, %), and (bottom) fat fraction (%) for all 31 patients across twenty muscles. Each point is illustrated by a grey dot, and the average is shown as a black horizontal bar. (B) Examples of STIR content and fat fraction along the length of the muscle (distal to proximal, %). The examples shown are three different patient’s tibialis anterior, in which the STIR content (purple) found at baseline is displayed as compared to their fat fraction at baseline (solid black line) and fat infiltration 1 year later (dotted black line). Displayed are three different relationships: (top) fat infiltration increases with progression but there is no STIR content at baseline; (middle) fat infiltration increases with progression and there is corresponding STIR content at baseline; (bottom) no fat infiltration increases over time but there is STIR content at baseline.
