Table 1 Comparison of demographic and blood parameters of the children.

From: Development and validation of a diagnostic prediction model for children with pertussis

Variables

Pertussis (n = 299)

Non-pertussis (n = 178)

P value

Training set (n = 357)

Validation set (n = 120)

P value

Age (months)

48.00 (5.00–72.00)

36.00 (12.00–72.00)

0.119

36.00 (7.00–72.00)

46.00 (7.75–72.00)

0.887

Male gender, n (%)

144 (48.16)

85 (47.75)

0.931

167 (46.78)

62 (51.67)

0.354

Urban region, n (%)

183 (61.20)

130 (73.03)

0.009

233 (65.27)

80 (66.67)

0.780

Vaccinate, n (%)

254 (84.95)

163 (91.57)

0.035

312 (87.39)

105 (87.50)

0.976

Epidemiological history, n (%)

13 (4.35)

2 (1.12)

0.051

9 (2.52)

6 (5.00)

0.297

WBC (× 109/L)

11.13 (8.58–14.46)

9.22 (6.69–11.87)

 < 0.001

10.51 (7.85–13.57)

10.29 (7.37–13.94)

0.565

RBC (× 1012/L)

4.44 (4.16–4.73)

4.40 (4.13–4.72)

0.341

4.41 (4.13–4.72)

4.47 (4.20–4.72)

0.279

HGB (g/L)

119.33 ± 10.80

119.17 ± 10.34

0.879

119.22 ± 10.70

119.42 ± 10.42

0.862

HCT (%)

37.62 ± 3.12

36.81 ± 3.16

0.007

37.31 ± 3.20

37.34 ± 3.03

0.909

PLT (× 109/L)

364.00 (275.50–457.50)

328.00 (246.25–393.75)

0.002

343.00 (270.00–428.00)

362.50 (243.50–433.50)

0.881

NEUT (%)

33.90 (21.40–46.45)

47.35 (30.05–62.65)

 < 0.001

39.40 (23.20–53.90)

38.40 (24.45–50.00)

0.716

LYMPH (%)

54.00 (41.80–67.80)

41.30 (27.75–57.10)

 < 0.001

48.20 (34.90–65.00)

50.15 (38.57–63.25)

0.728

MONO (%)

6.60 (5.50–8.55)

7.80 (6.00–9.80)

 < 0.001

7.10 (5.60–9.00)

7.30 (5.80–9.00)

0.492

MCV (fl)

85.10 (82.35–87.95)

84.50 (80.95–87.30)

0.023

85.00 (81.90–87.90)

84.90 (81.95–87.35)

0.712

MCH (pg)

28.10 (26.75–29.30)

27.50 (26.20–28.50)

0.002

27.90 (26.40–29.00)

27.75 (26.80–28.92)

0.961

MCHC (g/L)

324.00 (313.00–337.00)

324.00 (316.00–332.00)

0.649

324.00 (314.00–335.00)

323.00 (315.00–333.25)

0.802

NLR

0.64 (0.31–1.10)

1.15 (0.52–2.26)

 < 0.001

0.81 (0.36–1.54)

0.78 (0.39–1.27)

0.717

LMR

7.52 (5.09–10.91)

5.06 (3.26–8.30)

 < 0.001

6.57 (4.24–9.78)

6.73 (4.22–9.45)

0.798

PLR

59.28 (41.73–88.14)

88.81 (62.11–133.65)

 < 0.001

70.94 (48.79–103.66)

68.31 (47.23–103.69)

0.801

PLT-MPV-R

35.00 (26.84–46.50)

32.50 (23.83–40.98)

0.018

32.98 (26.04–44.11)

35.58 (23.67–46.25)

0.708

PDW-MPV-R

1.16 (1.06–1.33)

1.07 (1.01–1.17)

 < 0.001

1.13 (1.04–1.26)

1.10 (1.01–1.27)

0.176

CRP (mg/L)

0.32 (0.10–1.19)

1.75 (0.41–11.30)

 < 0.001

0.60 (0.15–3.49)

0.57 (0.12–4.20)

0.662

  1. WBC, white blood cell; RBC, red blood cell; HGB, haemoglobin; HCT, haematocrit; PLT, platelet; NEUT, neutrophil; LYMPH, lymphocyte; MONO, monocyte; MCV, mean red blood cell volume; MCH, mean red blood cell haemoglobin; MCHC, mean red blood cell hemoglobin concentration; NLR, neutrophil to lymphocyte ratio; LMR, lymphocyte to monocyte ratio; PLR, platelet to lymphocyte ratio; PLT-MPV-R, platelet to mean platelet volume ratio; PDW-MPV-R, platelet distribution width to mean platelet volume ratio; CRP, C-reactive protein.
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