Figure 4
From: Prognostic relevance of high expression of kynurenine pathway markers in glioblastoma
Kaplan–Meier survival curves showing the correlation between cytoplasmic TDO2 (A), IDO1 (B), IDO2 (C) and nuclear AhR (D) expression and overall survival of newly diagnosed IDHwt glioblastoma patients. Patients with H-scoring of TDO2, IDO1/2 and AhR equal or above determined cut-offs are displayed with red lines, patients below these cut-off values are shown with dark lines. TDO2 tryptophan 2,3-dioxygenase, IDO1 indoleamine 2,3-dioxygenase 1, IDO2 indoleamine 2,3-dioxygenase 2, AhR aryl hydrocarbon receptor.
