Figure 1

T1 maps (seconds) at baseline, the permeability-surface area product (PS; min−1), and fractional plasma volume (\({v}_{p}\)) for an example participant. The T1 maps were obtained using the variable flip angle method, and PS and \({v}_{p}\) were obtained using Patlak analysis. Note that while the images are thresholded according to the color bars to aid visualization, no thresholding or exclusion based on extreme values was used for any of the results.