Table 3 Associations between P1NP and ALP on one side and variables associated with osteoporosis.

From: Changes in bone turnover markers 6–12 months after bariatric surgery

Dependent variables

 

ALP (U/L)

Leptin (pmol/L)

Adiponectin (mg/L)

PTH (pmol/L)

iCa (mmol/L)

Phosphate (mmol/L)

P1NP (microg/L)

0.43

(0.29; 0.64)

p < 0.001

0.002

(− 0.006; 0.006)

p = 0.544

− 0.28

(− 0.86; 0.98)

p = 0.492

2.58

(0.83; 4.08)

p = 0.001

− 32

(− 150; 24)

p = 0.528

2.7

(− 18.5; 20.7)

p = 0.781

ALP (U/L)

 

− 0.002

(− 0.011; 0.003)

p = 0.632

− 0.62

(− 1.49; 0.45)

p = 0.189

2.12

(0.42; 3.80)

p = 0.017

− 23

(− 107; 73)

p = 0.610

− 4.8

(− 17.7; 8.3)

p = 0.488

  

Mg (mmol/L)

Vitamin D (nmol/L)

Vitamin B6 (nmol/L)

FT4 (pmol/L)

TSH (mU/L)

P1NP

(microg/L)

 

8.7

(− 38.9; 50.8)

p = 0.705

− 0.08

(− 0.24; 0.04)

p = 0.259

0.00

(− 0.10; 0.10)

p = 0.933

− 0.32

(− 1.86; 0.62)

p = 0.527

− 1.39

(− 4.24; 0.84)

p = 0.258

ALP (U/L)

 

30.9

(− 4.5; 65.6)

p = 0.095

− 0.01

(− 0.11; 0.10)

p = 0.872

0.016

(− 0.050; 0.097)

p = 0.669

− 0.06

(− 1.12; 0.59)

p = 0.883

− 1.28

(− 4.19; 0.65)

p = 0.291

  1. The analyses were performed with a linear mixed regression model based on 10,000 bootstrap samples with P1NP and ALP, one at a time, as dependent variables, and one by one of Leptin, Adiponectin, PTH, iCa, Ph, Mg Vitamin D, Vitamin B6, FT4 and TSH as independent variables adjusted for age, sex, point of time, surgical method, APOE-Ɛ3, BMI, smoking habits, diabetes, and CRP. Results are given as estimates (B-values) with 95% confidence intervals (percentiles) and p-values. Statistically significant p-values in bold text.
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