Table 3 Univariate and multivariate Cox regression analysis of clinicopathological parameters and prognosis in patients with cervical cancer.

From: NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer

Parameter

n

Univariate regression

Multivariate regression

HR

96% CI

p

HR

96% CI

p

Age (year)

    

9.156

3.35–25.05

0.000

 ≤ 45

58

6.26

2.42–16.23

0.000

   

 > 45

61

      

TNM stage

       

 TNM 1

67

10.76

3.78–30.63

0.000

12.59

4.30–36.05

0.000

 TNM 2–4

52

      

T stage

       

 T1

67

10.76

3.78–30.63

0.000

   

 T2-4

52

      

N stage

       

 N0

97

4.76

2.38–19.50

0.000

   

 N1

22

      

M stage

   

–

   

 M1

119

      

 M2

0

      

Lymph node status

       

 No

97

4.76

2.381–9.497

0.000

   

 Metastasis

22

      

Recurrence

       

 Present

39

387.75

7.58–19,848.31

0.003

   

 Absent

80

      

NLRC5 level

    

0.24

0.10–0.53

0.000

 Low

60

0.46

0.22–0.96

0.037

   

 High

59

      

LC3 level

       

 Low

60

0.84

0.42–1.68

0.626

   

 High

59

      

Beclin level

 Low

60

0.83

0.42–1.66

0.602

   

 High

59

      

Histological subtype

 Squamous

arcinoma

110

1.20

0.36–3.92

0.769

   

 Others

8

      

HPV

 Uninfected

16

      

 High-risk type

57

1.56

0.54–4.50

0.408

   

 High-risk

46

0.25

0.06–1.01

0.051

   
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