Table 1 Clinical data in painless vs. painful diabetic neuropathy in 190 patients.

From: Eleven neurology-related proteins measured in serum are positively correlated to the severity of diabetic neuropathy

 

Painless neuropathy

n = 96

Painful neuropathy

n = 94

p-value

Age (years)

72 (67–78)

71 (61–76)

0.042*

Sex (% females)

30%

30%

0.950

BMI (kg/m2)

27.7 (25.1–31.4)

30.7 (27.2–35.2)

 < 0.001*

HbA1c %

7.1 (6.5–7.8)

7.9 (7.0–8.8)

0.002*

Type 2 diabetes %

92%

91%

0.965

TCSS

8 (6–11)

13 (10–16)

 < 0.001*

DN4

2 (1–3)

6 (4–7)

 < 0.001*

BPI pain average

N.A.

6 (4–7)

N.A.

BPI worst

N.A.

8 (6–8)

N.A.

BPI least

N.A.

3 (2–5)

N.A.

BPI now

N.A.

5 (3–7)

N.A.

BPI severity subscore

N.A.

5.3 (4–6.5)

N.A.

NPSI total

N.A.

7 (4.2–11.6)

N.A.

PainDetect

N.A.

18 (12.5–22)

N.A.

  1. Data are expressed as median (25th–75th percentiles) except for sex.
  2. BMI, Body Mass Index; TCSS, Toronto Clinical Scoring System; DN4, Douleur Neuropathique en 4 Questions; BPI, Brief Pain Inventory 0–10; NPSI total, Neuropathic Pain Symptoms Inventory, total value.
  3. *Denotes statistical significance at the 0.05 level.
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