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Figure 2

From: Entinostat as a combinatorial therapeutic for rhabdomyosarcoma

Figure 2

(A) Illustrative representation of entinostat pharmacokinetics in humans derived from clinical trial and preclinical data17. (B) Illustrative representation of entinostat pharmacokinetics in mice derived from clinical and preclinical data. (C) Patient derived xenograft mouse models of rhabdomyosarcoma (CTG-1008, CTG-1916, CTG-2127 and CTG1213). (D) Chemical structure of entinostat. (E) Chemical structure of mocetinostat. (illustration by Sun Young Park).

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