Table 2 Distribution of transmitted drug resistance according to ARV classes and demographic characteristics of the Angolan naïve patients.
Independent variable | N (%) | NRTI mutation | NNRTI mutation | PI mutation | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
No (%) | Yes (%) | p-value | No (%) | Yes (%) | p-value | No (%) | Yes (%) | p-value | ||
Overall | 45 (100) | 44 (97.8) | 1 (2.2) | 36 (80.0) | 9 (20.0) | 44 (97.8) | 1 (2.2) | |||
Age distribution | ||||||||||
≤ 30 years | 19 (42.2) | 19 (100) | 0 (0.0) | 1.000 | 13 (68.4) | 6 (31.6) | 0.137 | 18 (94.7) | 1 (5.3) | 0.422 |
> 30 years | 26 (57.8) | 25 (96.2) | 1 (3.8) | 23 (88.5) | 3 (11.5) | 26 (100) | 0 (0.0) | |||
Sex | ||||||||||
Female | 5 (11.1) | 5 (100) | 0 (0.0) | 1.000 | 4 (80.0) | 1 (20.0) | 1.000 | 5 (100) | 0 (0.0) | 1.000 |
Male | 40 (88.9) | 39 (97.5) | 1 (2.5) | 32 (80.0) | 8 (20.0) | 39 (97.5) | 1 (2.5) | |||
Residence área | ||||||||||
Non-urbanized | 23 (51.1) | 23 (100) | 0 (0.0) | 0.489 | 18 (78.3) | 5 (21.7) | 0.766 | 23 (100) | 0 (0.0) | 0.489 |
Urbanized | 22 (48.9) | 21 (95.5) | 1 (4.5) | 18 (81.8) | 4 (18.2) | 21 (95.5) | 1 (4.5) | |||
Occupation | ||||||||||
Unemployed | 8 (17.8) | 7 (87.5) | 1 (12.5) | 0.030 | 6 (75.0) | 2 (25.0) | 0.651 | 8 (100) | 0 (0.0) | 0.638 |
Employed | 37 (82.2) | 37 (100) | 0 (0.0) | 30 (81.1) | 7 (18.9) | 36 (97.3) | 1 (2.7) | |||
HIV-1 subtypes | ||||||||||
C | 16 (35.6) | 16 (100) | 0 (0.0) | 0.593 | 11 (68.8) | 5 (31.3) | 0.609 | 15 (93.8) | 1 (6.3) | 0.967 |
F1 | 7 (15.6) | 6 (85.7) | 1 (14.3) | 5 (71.4) | 2 (28.6) | 7 (100) | 0 (0.0) | |||
G | 5 (11.1) | 5 (100) | 0 (0.0) | 5 (100) | 0 (0.0) | 5 (100) | 0 (0.0) | |||
A1 | 5 (11.1) | 5 (100) | 0 (0.0) | 4 (80.0) | 1 (20.0) | 5 (100) | 0 (0.0) | |||
H | 3 (6.7) | 3 (100) | 0 (0.0) | 2 (66.7) | 1 (33.3) | 3 (100) | 0 (0.0) | |||
D | 2 (4.4) | 2 (100) | 0 (0.0) | 2 (100) | 0 (0.0) | 2 (100) | 0 (0.0) | |||
CRF02_AG | 2 (4.4) | 1 (100) | 0 (0.0) | 2 (100) | 0 (0.0) | 2 (100) | 0 (0.0) | |||
Other HIV-1 strains | 5 (11.1) | 5 (100) | 0 (0.0) | 5 (100) | 0 (0.0) | 5 (100) | 0 (0.0) | |||
