Table 2 Relationships between PON risk with the anesthesia groups (TIVA or volatile anesthesia) and other factors using uni- and multivariate logistic regression analyses.
|  | PON +  | PON- | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
(n = 37) | (n = 45) | OR (95% CI) | P value | OR (95% CI) | P value | |
Anesthesia | Â | Â | Â | 0.002* | Â | 0.011* |
  TIVA | 16 (43.2%) | 35 (77.8%) | Reference |  | Reference |  |
  Volatile anesthetics | 21 (56.8%) | 10 (22.2%) | 4.59 (1.76–11.97) |  | 5.33 (1.47–19.36) |  |
Sex | Â | Â | Â | 0.831 | Â | 0.492 |
  Male | 14 (37.8%) | 16 (35.6%) | Reference |  | Reference |  |
  Female | 23 (62.2%) | 29 (64.4%) | 0.91 (0.37–2.23) |  | 1.58 (0.43–5.87) |  |
Smoking | Â | Â | Â | 0.456 | Â | 0.343 |
  Yes | 3 (8.1%) | 6 (13.3%) | Reference |  | Reference |  |
  No | 34 (91.9%) | 39 (86.7%) | 1.74 (0.40–7.51) |  | 2.31 (0.41–12.94) |  |
Age | 25.5 | 25.8 | 1.00 (0.95–1.04) | 0.899 | 0.99 (0.93–1.06) | 0.793 |
BMI (kg/m2) | 21.3 | 21.4 | 0.98 (0.82–1.17) | 0.853 | 1.04 (0.80–1.34) | 0.778 |
Surgical time (min) | 176.3 | 173.5 | 1.00 (0.99–1.02) | 0.712 |  |  −  |
Anesthesia time (min) | 298.5 | 299.6 | 1.00 (0.99–1.01) | 0.904 | 1.00 (0.98–1.02) | 0.890 |
Use of opioids | ||||||
  Fentanyl (μg) | 306.1 | 278.9 | 1.21 (0.92–1.60) | 0.168 | 1.22 (0.88–1.71) | 0.239 |
  Remifentanil (μg) | 4539.6 | 4908.6 | 0.98 (0.95–1.01) | 0.230 | 0.99 (0.93–1.05) | 0.786 |
In–Out balance | 1367.2 | 1340.8 | 1.01 (0.93–1.09) | 0.840 |  |  −  |
Infusion (mL) | 2363.7 | 2633.9 | 0.95 (0.89–1.01) | 0.098 | 0.94 (0.85–1.04) | 0.227 |
Out (mL) | 996.5 | 1293 | 0.91 (0.83–1.00) | 0.041* |  |  −  |
  Bleeding (mL) | 273.9 | 242.4 | 1.01 (0.99–1.04) | 0.384 | 1.01 (0.97–1.05) | 0.745 |
  Urine (mL) | 722.6 | 1050.7 | 0.89 (0.81–0.98) | 0.023* | 0.97 (0.83–1.12) | 0.655 |
