Table 1 Baseline characteristics of participants grouped according to different serum chloride.

From: L-shaped association between serum chloride levels with 90-day and 365-day all-cause mortality in critically ill patients with COPD: a retrospective cohort study

 

Serum chloride

P

Total (n = 2596)

Q1 (n = 639)

Q2 (n = 625)

Q3 (n = 673)

Q4 (n = 659)

Age, years

72.00 (64.00–80.00)

72.00 (63.00–80.00)

71.00 (63.00–80.00)

72.00 (64.00–79.00)

73.00 (66.00–81.50)

0.013

Gender, n (%)

     

0.189

 Male

1360 (52.39)

313 (48.98)

343 (54.88)

359 (53.34)

345 (52.35)

 

 Female

1236 (47.61)

326 (51.02)

282 (45.12)

314 (46.66)

314 (47.65)

 

Weight, kg

78.38 (65.00–95.11)

80.00 (64.00–100.00)

80.00 (65.00–96.90)

78.60 (65.60–94.50)

75.80 (63.40–89.80)

0.001

WBC, K/µL

11.50 (8.40–15.28)

10.80 (7.97–14.48)

11.40 (8.10–15.23)

11.51 (8.47–15.60)

12.08 (9.25–15.77)

 < 0.001

RBC, K/µL

3.49 (3.04–4.01)

3.62 (3.06–4.11)

3.57 (3.07–4.09)

3.52 (3.10–4.01)

3.35 (2.97–3.74)

 < 0.001

Platelet, K/µL

189.50 (140.46–253.00)

203.50 (148.12–282.00)

198.50 (148.00–261.67)

188.50 (143.75–240.00)

167.67 (129.79–224.17)

 < 0.001

Hemoglobin, g/dL

10.38 (8.90–11.80)

10.40 (8.91–12.09)

10.60 (9.00–12.10)

10.55 (9.13–11.90)

10.00 (8.80–11.27)

 < 0.001

RDW, %

14.75 (13.70–16.30)

15.00 (13.91–16.90)

14.80 (13.77–16.35)

14.48 (13.50–16.05)

14.75 (13.60–16.02)

 < 0.001

Sodium, mmol/L

139.00 (136.00–141.33)

135.00 (131.67–138.33)

138.00 (135.67–140.00)

139.33 (137.33–141.50)

141.00 (139.00–143.50)

 < 0.001

Potassium, mmol/L

4.28 (3.95–4.68)

4.30 (3.99–4.80)

4.30 (3.97–4.68)

4.27 (3.92–4.61)

4.23 (3.93–4.60)

0.011

Calcium, mmol/L

8.40 (8.00–8.80)

8.65 (8.19–9.02)

8.47 (8.00–8.80)

8.40 (8.00–8.80)

8.14 (7.80–8.50)

 < 0.001

Glucose, mmol/L

130.00 (110.00–163.04)

140.00 (113.00–178.75)

134.00 (111.25–168.50)

127.50 (109.00–156.00)

125.00 (107.00–151.00)

 < 0.001

PT, sec

13.90 (12.40–16.40)

14.00 (12.40–17.66)

13.88 (12.30–16.15)

13.75 (12.27–15.95)

13.98 (12.66–16.14)

0.016

PTT, sec

32.60 (28.10–43.16)

34.07 (28.48–47.81)

33.60 (28.45–43.83)

32.00 (27.80–42.05)

31.13 (27.98–38.93)

 < 0.001

BUN, mg/dL

21.00 (14.73–34.00)

24.50 (16.41–42.05)

20.50 (14.00–31.00)

19.50 (14.00–30.33)

21.00 (14.12–35.67)

 < 0.001

sCR, mg/dL

1.00 (0.70–1.47)

1.05 (0.70–1.86)

1.00 (0.70–1.40)

0.93 (0.70–1.32)

1.00 (0.77–1.50)

 < 0.001

SOFA

4.00 (2.00–7.00)

4.00 (2.00–7.00)

4.00 (2.00–7.00)

4.00 (2.00–7.00)

5.00 (3.00–8.00)

 < 0.001

APS III

42.00 (32.00–55.00)

46.00 (34.00–58.00)

42.00 (33.00–53.00)

40.00 (31.00–51.00)

42.00 (32.00–56.00)

 < 0.001

SIRS

3.00 (2.00–3.00)

3.00 (2.00–3.00)

3.00 (2.00–3.00)

3.00 (2.00–3.00)

3.00 (2.00–3.00)

0.061

SAPS II

37.00 (30.00–45.00)

37.00 (29.00–45.00)

36.00 (29.00–44.00)

36.00 (29.00–44.00)

39.00 (32.00–47.50)

 < 0.001

SBP, mmHg

114.55 (106.14–126.13)

116.57 (106.19–127.94)

115.56 (106.50–127.23)

114.86 (106.48–125.99)

112.04 (104.95–123.31)

0.004

DBP, mmHg

63.28 (57.32–70.00)

63.83 (57.56–70.61)

65.00 (59.27–71.79)

63.08 (57.75–70.08)

61.30 (55.55–68.00)

 < 0.001

Hypertension, n (%)

1042 (40.14)

230 (35.99)

261 (41.76)

292 (43.39)

259 (39.30)

0.038

Diabetes, n (%)

860 (33.13)

230 (35.99)

215 (34.40)

224 (33.28)

191 (28.98)

0.047

Heart failure, n (%)

1134 (43.68)

356 (55.71)

268 (42.88)

271 (40.27)

239 (36.27)

 < 0.001

Myocardial infarction, n (%)

334 (12.87)

87 (13.62)

74 (11.84)

90 (13.37)

83 (12.59)

0.776

CKD, n (%)

617 (23.77)

165 (25.82)

133 (21.28)

138 (20.51)

181 (27.47)

0.006

Stroke, n (%)

233 (8.98)

57 (8.92)

54 (8.64)

61 (9.06)

61 (9.26)

0.984

Hyperlipidemia, n (%)

1192 (45.92)

266 (41.63)

266 (42.56)

333 (49.48)

327 (49.62)

0.002

90-day mortality, n (%)

657 (25.31)

211 (33.02)

142 (22.72)

142 (21.10)

162 (24.58)

 < 0.001

365-day mortality, n (%)

941 (36.25)

306 (47.89)

202 (32.32)

214 (31.80)

219 (33.23)

 < 0.001

  1. Continuous variables are expressed using medians (quartiles) and categorical variables are expressed using numbers (percentages).
  2. WBC, white blood cell; RBC, red blood cell; RDW, red blood cell distribution; PT, prothrombin time; PTT, partial thromboplastin time; BUN, blood urea nitrogen; sCR, serum creatinine; SOFA, sequential organ failure assessment; APS III, acute physiology score III; SIRS, systemic inflammatory response syndrome; SAPS II, simplified acute physiology score II; SBP, systolic blood pressure; DBP, diastolic blood pressure; CKD, chronic kidney disease.