Table 4 Subgroup analysis of serum chloride and 90-day and 365-day mortality in COPD critically ill patients.

From: L-shaped association between serum chloride levels with 90-day and 365-day all-cause mortality in critically ill patients with COPD: a retrospective cohort study

 

90-day mortality

365-day mortality

95% CI

P

P for interaction

95% CI

P

P for interaction

Age, years

  

0.675

  

0.575

 ≥ 72

0.95 (0.93, 0.97)

 < 0.001

 

0.95 (0.93, 0.97)

 < 0.001

 

 < 72

0.98 (0.95, 1.01)

0.137

 

0.97 (0.94, 0.99)

0.008

 

Gender

  

0.731

  

0.611

 Male

0.95(0.93, 0.98)

 < 0.001

 

0.95 (0.93, 0.97)

 < 0.001

 

 Female

0.96 (0.94, 0.99)

0.003

 

0.97 (0.95, 0.99)

0.002

 

Weight, kg

  

0.889

  

0.901

 < 78.38

0.95 (0.93, 0.97)

 < 0.001

 

0.95 (0.93, 0.97)

 < 0.001

 

 ≥ 78.38

0.98 (0.95, 1.00)

0.100

 

0.97 (0.95, 0.99)

0.006

 

Hypertension

  

0.431

  

0.977

 No

0.96 (0.94, 0.98)

 < 0.001

 

0.96 (0.95, 0.98)

 < 0.001

 

 Yes

0.98 (0.95, 1.02)

0.272

 

0.96 (0.93, 0.98)

0.002

 

Diabetes

  

0.931

  

0.877

 No

0.95 (0.93, 0.97)

 < 0.001

 

0.95 (0.93, 0.96)

 < 0.001

 

 Yes

1.00 (0.97, 1.04)

0.828

 

0.99 (0.97, 1.02)

0.688

 

Heart failure

  

0.499

  

0.202

 No

0.96 (0.93, 0.99)

0.003

 

0.95 (0.93, 0.97)

 < 0.001

 

 Yes

0.96 (0.94, 0.98)

0.002

 

0.96 (0.94, 0.98)

 < 0.001

 

Myocardial infarction

  

0.220

  

0.098

 No

0.96 (0.94, 0.98)

 < 0.001

 

0.96 (0.94, 0.97)

 < 0.001

 

 Yes

0.94 (0.89, 1.00)

0.040

 

0.96 (0.91, 1.00)

0.062

 

CKD

  

0.424

  

0.209

 No

0.96 (0.94, 0.98)

 < 0.001

 

0.95 (0.93, 0.97)

 < 0.001

 

 Yes

0.97 (0.94, 1.01)

0.123

 

0.98 (0.96, 1.01)

0.224

 

Stroke

  

0.200

  

0.200

 No

0.96 (0.95, 0.98)

 < 0.001

 

0.96 (0.94, 0.98)

 < 0.001

 

 Yes

0.93 (0.85, 1.01)

0.087

 

0.95 (0.89, 1.01)

0.123

 
  1. Age and weight were grouped according to the median.
  2. The interaction p is calculated according to the multiplicative interaction.
  3. CKD: chronic kidney disease.