Figure 3

Levels of Factor VIII (a), VWF antigen (b) ADAMTS-13 activity (c), and VWF antigen: ADAMTS-13 ratio (b) in patients undergoing plasma exchange (PEX) and patients receiving standard of care (SoC) only. All ‘pre-PEX’ levels were taken immediately before PEX, and post- PEX levels were taken immediately after PEX. If patients were no longer undergoing PEX, their data are provided as ‘follow up’ (F/U) values, taken at pre-specified time points. Patients in the control group had blood samples taken at the same time points and values represented in the same graph. Results displayed as box and whisker plots with median values, interquartile range, and 95% confidence intervals for each time point, with individual patient data represented as a datapoint.