Figure 5
From: Immunological assay using a solid-state pore with a low limit of detection
Quantitative analysis of PSA using Adapore. Polystyrene beads were modified with an anti-PSA antibody. (a) Dependence of pulse frequency on PSA concentration. Error bars indicate SD. (b) Dependence of the pulse height (Ip) histogram of the ionic current–time waveform on PSA concentration. Each concentration was measured using three solid-state pore modules. (c) Dependence of aggregation on PSA concentration. For each concentration, measurements were made using three solid-state pore modules. Error bars indicate ± 3 SD. The dotted line denotes the mean ± 3 SD of the negative control (PSA concentration: 0 fM).
