Table 1 Cervical cord morphometry.

From: Progressive cervical cord atrophy parallels cognitive decline in Alzheimer’s disease

MRI parameter

Estimated mean per level

AD—CN

CN

SE

AD

SE

Differences

P value

CSA [mm2]

     

%

 

 C1

69.6

0.5

63.2

0.6

− 6.4

− 9.2

 < 0.001

 C2

64.9

0.5

59.2

0.5

− 5.7

− 8.8

 < 0.001

 C3

60.2

0.7

55.1

0.7

− 5.1

− 8.5

 < 0.001

A–P width [mm]

 C1

8.06

0.06

7.62

0.06

− 0.44

− 5.46

 < 0.001

 C2

7.47

0.06

7.16

0.06

− 0.31

− 4.15

 < 0.001

 C3

6.89

0.08

6.71

0.08

− 0.18

− 2.61

0.062

L–R width [mm]

 C1

11.0

0.1

10.6

0.1

− 0.4

− 3.6

0.002

 C2

11.1

0.1

10.5

0.1

− 0.6

− 5.4

 < 0.001

 C3

11.2

0.1

10.5

0.2

− 0.7

− 6.2

0.001

Hippocampus [mm3]

 L

2134

43.6

1688

63.4

− 446

20.9%

 < 0.001

 R

2187

53.8

1751

71.0

− 436

19.9%

 < 0.001

  1. Analysis of cross-sectional structural MRI data with spinal cord toolbox (SCT) shows significant differences in spinal cord area, left–right (L-R) width, and anterior–posterior (A-P) width between Alzheimer's disease (AD) patients and cognitively normal (CN) subjects.
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