Figure 6
From: Pituitary-derived small extracellular vesicles promote liver repair by its cargo miR-143-3p
Wild-type pituitary sEV relieves liver injury in the miR-143 knockout mouse model by its cargo miR-143-3p. (a) Ex vivo imaging of major organs dissected after i.v. injection (b) Representative H&E staining images of the miR-143 KO mice livers from different groups. (c) Serum ALT levels (d) Serum AST levels. (e) Serum IGFBP5 levels. (f) Serum IGF-1 levels. (g) Relative expression of miR-143-3p after different treatment. (h) mRNA expression quantified by qRT-PCR (n = 6). (i)Western blot analysis of PCNA, IGFBP5, IGF-1 proteins in the livers of 143 KO mice from each group (n = 6).
