Table 1 Distribution of genotypes in the offspring of each generation.

From: Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster

Generation of parents

No. of offspring

Genotype of offspring (%)

Male

Female

+/+

+/−

−/−

F1

7

6

7

6

0

F2

13

11

9

15

0

F3

14

20

16

13

5

F4

11

6

11

16

0

F5

16

23

14

20

4

F6

34

30

16

45

5

F7

34

29

26

29

8

Total

129

125

101 (37.8)

144 (53.9)

22* (8.2)

  1. *P < 0.0001 (vs. expected number, χ2-test).
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