Table 2 Relationships between log BNP and other clinical parameters by linear regression analyses.

From: Plasma B-type natriuretic peptide is independently associated with cardiovascular events and mortality in patients with chronic kidney disease

Variables

Simple linear regression analyses

Multiple linear regression analyses

Coefficients

95% CI

P

Coefficients

95% CI

P

Age (years)

0.042

(0.038, 0.047)

 < 0.01

0.017

(0.012, 0.021)

 < 0.01

Male

0.179

(0.020, 0.338)

0.03

 − 0.142

(− 0.270, − 0.014)

0.03

Smoking

0.219

(0.067, 0.371)

0.01

 − 0.005

(− 0.120, 0.110)

0.94

Diabetes mellitus

0.444

(0.287, 0.601)

 < 0.01

 − 0.351

(− 0.149, 0.079)

0.55

Dyslipidemia

 − 0.127

(− 0.296, 0.042)

0.14

 − 0.359

(− 0.473, − 0.244)

 < 0.01

Prior CVDs

1.095

(0.950, 1.240)

 < 0.01

0.304

(0.187, 0.422)

 < 0.01

Malignancy

0.661

(0.388, 0.934)

 < 0.01

0.095

(− 0.083, 0.273)

0.30

RAAS inhibitors

0.495

(0.342, 0.648)

 < 0.01

 − 0.100

(− 0.212, 0.012)

0.08

β-blockers

1.073

(0.887, 1.259)

 < 0.01

0.527

(0.395, 0.660)

 < 0.01

Diuretics

0.877

(0.714, 1.041)

 < 0.01

0.196

(0.076, 0.315)

 < 0.01

Systolic blood pressure (mm Hg)

0.024

(0.019, 0.028)

 < 0.01

0.009

(0.005, 0.012)

 < 0.01

BMI (kg/m2)

 − 0.053

(− 0.072, − 0.034)

 < 0.01

 − 0.058

(− 0.073, − 0.043)

 < 0.01

CRP (mg/L)

0.020

(0.005, 0.035)

0.01

0.002

(− 0.007, 0.012)

0.65

Hemoglobin (g/dL)

 − 0.290

(− 0.320, − 0.261)

 < 0.01

 − 0.094

(− 0.126, − 0.001)

 < 0.01

Serum albumin (g/dL)

 − 0.680

(− 0.799, − 0.562)

 < 0.01

 − 0.294

(− 0.413, − 0.175)

 < 0.01

Serum phosphorus (mg/dL)

0.180

(0.069, 0.290)

 < 0.01

 − 0.019

(− 0.100, 0.062)

0.64

eGFR (mL/min/1.73 m2)

 − 0.022

(− 0.025, − 0.019)

 < 0.01

 − 0.002

(− 0.005, 0.001)

0.24

Daily proteinuria (g)

0.076

(0.047, 0.106)

 < 0.01

0.012

(− 0.017, 0.041)

0.41

LVEF (%)

 − 0.036

(− 0.045, − 0.028)

 < 0.01

 − 0.017

(− 0.022, − 0.011)

 < 0.01

LAD (mm)

0.073

(0.064, 0.083)

 < 0.01

0.034

(0.026, 0.043)

 < 0.01

LVMI (g/m2)

0.015

(0.013, 0.016)

 < 0.01

0.005

(0.004, 0.006)

 < 0.01

  1. BNP B-type natriuretic peptide, CVD cardiovascular disease, RAAS renin–angiotensin–aldosterone system, BMI body mass index, CRP C-reactive protein, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, LAD left atrial diameter, LVMI left ventricular mass index.
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