Table 4 Adjusted hazard ratios for CV events per 1-log unit increment in log BNP among subgroups stratified by clinical parameters.
No. of patients | No. of events | HR (95% CI) | P | P for interaction | |
|---|---|---|---|---|---|
Age | |||||
Low (< 70.6 years) | 539 | 48 | 1.35 (0.97, 1.89) | 0.08 | 0.07 |
High (≥ 70.6 years) | 539 | 110 | 1.18 (0.94, 1.48) | 0.15 | |
Sex | |||||
Male | 695 | 114 | 1.32 (1.06, 1.63) | 0.01 | 0.14 |
Female | 383 | 44 | 1.44 (0.94, 2.19) | 0.09 | |
Diabetes mellitus | |||||
Absence | 698 | 85 | 1.38 (1.05, 1.81) | 0.02 | 0.06 |
Presence | 380 | 73 | 1.16 (0.89, 1.52) | 0.26 | |
Dyslipidemia | |||||
Absence | 306 | 36 | 1.60 (1.06, 2.41) | 0.03 | 0.20 |
Presence | 772 | 122 | 1.25 (1.01, 1.56) | 0.04 | |
Prior CVDs | |||||
Absence | 694 | 63 | 1.36 (1.004, 1.85) | 0.047 | 0.41 |
Presence | 384 | 95 | 1.19 (0.94, 1.51) | 0.14 | |
SBP | |||||
Low (< 131.8 mmHg) | 539 | 71 | 1.41 (1.05, 1.89) | 0.02 | 0.23 |
High (≥ 131.8 mmHg) | 539 | 87 | 1.20 (0.93, 1.55) | 0.15 | |
BMI | |||||
Low (< 22.9 kg/m2) | 539 | 86 | 1.33 (1.04, 1.72) | 0.03 | 0.45 |
High (≥ 22.9 kg/m2) | 539 | 72 | 1.18 (0.89, 1.56) | 0.26 | |
CRP | |||||
Low (< 0.9 mg/L) | 515 | 67 | 1.23 (0.91, 1.67) | 0.18 | 0.82 |
High (≥ 0.9 mg/L) | 563 | 91 | 1.27 (0.99, 1.63) | 0.06 | |
Serum albumin | |||||
Low (< 3.5 g/dL) | 528 | 85 | 1.18 (0.92, 1.51) | 0.19 | 0.39 |
High (≥ 3.5 g/dL) | 550 | 73 | 1.35 (1.01, 1.81) | 0.04 | |
eGFR | |||||
Low (< 30.3 mL/min/1.73 m2) | 539 | 90 | 1.20 (0.94, 1.54) | 0.14 | 0.84 |
High (≥ 30.3 mL/min/1.73 m2) | 539 | 68 | 1.24 (0.92, 1.69) | 0.16 | |
LVEF | |||||
Low (< 69.3%) | 534 | 82 | 1.08 (0.84, 1.39) | 0.53 | 0.28 |
High (≥ 69.3%) | 544 | 76 | 1.52 (1.15, 2.02) | < 0.01 | |
LAD | |||||
Low (< 39 mm) | 534 | 49 | 1.09 (0.76, 1.56) | 0.64 | 0.41 |
High (≥ 39 mm) | 544 | 109 | 1.34 (1.08, 1.68) | 0.01 | |
LVMI | |||||
Low (< 118.0 g/m2) | 539 | 50 | 1.43 (0.99, 2.08) | 0.06 | 0.32 |
High (≥ 118.0 g/m2) | 539 | 108 | 1.26 (1.00, 1.58) | 0.049 | |
