Table 5 Adjusted hazard ratios for composite events per 1-log unit increment in log BNP among subgroups stratified by clinical parameters.
No. of patients | No. of events | HR (95% CI) | P | P for interaction | |
|---|---|---|---|---|---|
Age | |||||
Low (< 70.6 years) | 539 | 60 | 1.42 (1.05, 1.92) | 0.02 | 0.06 |
High (≥ 70.6 years) | 539 | 188 | 1.11 (0.94, 1.32) | 0.23 | |
Sex | |||||
Male | 695 | 173 | 1.26 (1.06, 1.50) | 0.01 | 0.09 |
Female | 383 | 75 | 1.23 (0.90, 1.69) | 0.19 | |
Diabetes mellitus | |||||
Absence | 698 | 142 | 1.36 (1.10, 1.68) | < 0.01 | 0.09 |
Presence | 380 | 106 | 1.09 (0.88, 1.35) | 0.44 | |
Dyslipidemia | |||||
Absence | 306 | 63 | 1.27 (0.93, 1.74) | 0.13 | 0.41 |
Presence | 772 | 185 | 1.20 (1.00, 1.42) | 0.04 | |
Prior CVDs | |||||
Absence | 694 | 103 | 1.21 (0.94, 1.55) | 0.14 | 0.37 |
Presence | 384 | 145 | 1.18 (0.98, 1.42) | 0.08 | |
SBP | |||||
Low (< 131.8 mmHg) | 539 | 116 | 1.35 (1.08, 1.69) | < 0.01 | 0.18 |
High (≥ 131.8 mmHg) | 539 | 132 | 1.13 (0.92, 1.39) | 0.25 | |
BMI | |||||
Low (< 22.9 kg/m2) | 539 | 145 | 1.28 (1.05, 1.56) | 0.02 | 0.17 |
High (≥ 22.9 m2) | 539 | 103 | 1.12 (0.88, 1.41) | 0.36 | |
CRP | |||||
Low (< 0.9 mg/L) | 515 | 103 | 1.34 (1.05, 1.72) | 0.02 | 0.43 |
High (≥ 0.9 mg/L) | 563 | 145 | 1.14 (0.93, 1.38) | 0.20 | |
Serum albumin | |||||
Low (< 3.5 g/dL) | 528 | 143 | 1.21 (0.99, 1.46) | 0.06 | 0.62 |
High (≥ 3.5 g/dL) | 550 | 105 | 1.28 (1.00, 1.64) | 0.048 | |
eGFR | |||||
Low (< 30.3 mL/min/1.73 m2) | 539 | 151 | 1.10 (0.91, 1.32) | 0.34 | 0.86 |
High (≥ 30.3 mL/min/1.73 m2) | 539 | 97 | 1.31 (1.03, 1.67) | 0.03 | |
LVEF | |||||
Low (< 69.3%) | 534 | 133 | 1.17 (0.95, 1.44) | 0.14 | 0.80 |
High (≥ 69.3%) | 544 | 115 | 1.27 (1.02, 1.59) | 0.03 | |
LAD | |||||
Low (< 39 mm) | 534 | 87 | 1.04 (0.81, 1.34) | 0.78 | 0.52 |
High (≥ 39 mm) | 544 | 161 | 1.31 (1.09, 1.57) | < 0.01 | |
LVMI | |||||
Low (< 118.0 g/m2) | 539 | 80 | 1.27 (0.97, 1.67) | 0.09 | 0.47 |
High (≥ 118.0 g/m2) | 539 | 168 | 1.21 (0.999, 1.45) | 0.05 | |
