Table 2 Interaction force analysis of ICA and Keap1 molecular docking.

From: Icariin alleviates cisplatin-induced premature ovarian failure by inhibiting ferroptosis through activation of the Nrf2/ARE pathway

Interactions

Binding sites

Binding free energy (kcal/mol)

Hydrogen bond interaction

ASN414

SER363

ARG380

ARG415

−7.6

Electrostatic interaction

–

–

hydrophobic interaction

–

–

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