Table 1 Details of ML and DL architectures for ALL classification.

From: An attention-based deep learning for acute lymphoblastic leukemia classification

Reference no

Algorithm/architecture Deployed year

Approach

Drawbacks

5

SVM and K-NN (2017)

Machine Learning

Local binary Features were extracted where it failed to detect the overlapping and irregular cells

6

SVM (2015)

Feature-based detection where leukemia-infected regions were not detected accurately

8

Random Forest (2017)

Excelled in the classification of nucleus and cytoplasm, texture features can be overcome with color and morphological features for better performance. The time complexity is high due to the ensembling technique

22

k-means and watershed algorithms with PCA (2020)

This method has overcome the overfitting problem through multifractal features but results in time complexity

9

ViT-CNN (2021)

Deep Learning

Noise and data balance through vision transformer

10

CNN (2018)

Improved the classification for the subtypes using the morphology of L2 and L3 blasts Failed for overlapped cells

11

MobileNetV2 + ResNet18 (2021)

Poor performance is achieved for data split of 50% training and testing

32

YOLOv4 (2021)

colour fidelity, optimal brightness and contrast, resolution and general artefact reduction of microscopic blood smear images affect the accuracy

33

ALNett (2022)

Structural and contextual feature extraction has to be improved to improve accuracy

12

AlexNet + LeukNet (2021)

Feature extraction is not performed where the dataset is small

37

CNN + GAN (2022)

Data augmentation is required to generate additional instances

39

CNN + ML + Transfer Learning (e.g. ResNet50 combined with Random Forest)

Hybrid

Performance depends upon the choice of machine learning algorithm