Figure 7
KEGG enrichment analysis and validation of the intestinal immune network for IgA production between the CON group and the FMTi group. (a) KEGG enrichment analysis of the ileum transcriptome on day 1450,51,52. n = 5. (b) FPKM values and relative gene expressions of CD28, CTLA4, and CD4 were compared on day 14. n = 5. (c) The gene expression of CD28 and CTLA4 in the ileum and the expression levels of genes (IL-10, TGF-β, CXCL12, and CXCR4) related to the intestinal immune network for IgA production on days 7 and 14. n = 5. (d) The expression of IgA-positive cells in the ileum on days 7 and 14. n = 10. Bar = 50 μm. *P < 0.05, **P < 0.01, ***P < 0.001, versus the CON group.
