Figure 3
From: All organic nanomedicine for PDT–PTT combination therapy of cancer cells in hypoxia

Characteristics of Combi and PTT NPs. (a) TEM image of PTT (left) and Combi (right) NPs. Scale bars represent 100 nm. (b) Results of singlet oxygen detection test upon monochromatic light illumination (635 nm monochromatic Xe lamp (0.2 mW/cm2 at 635 nm)). (c) Cell viability assay evaluating material toxicity. Bars represent mean ± SD (n = 5). Statistical significance was determined using One-Way ANOVA; significant differences were observed among 9 groups, F(8,36) = 19.7889, p < 0.05. (d) Hypoxic test with DCFH-DA staining. Bars indicate mean ± SD (n = 4). The statistical significance was analyzed using a Student’s T-test: *p < 0.05.