Table2 Univariate analysis and multivariate analysis of the correlation of risk score with outcomes among lung adenocarcinoma patients in two cohorts.

From: Myeloid cell differentiation-related gene signature for predicting clinical outcome, immune microenvironment, and treatment response in lung adenocarcinoma

Variable

Univariate cox analysis

Multivariate cox analysis

HR (95% CI)

Pvalue

HR (95% CI)

Pvalue

TCGA-LUAD (overall survival)

Age

1.293 (0.902–1.851)

0. 161

1.584 (1.017–2.467)

0.042

Gender

0.945 (0.662–1.350)

0.757

0.785 (0.505–1.219)

0.281

T

1.563 (1.252–1.951)

 < 0.001

1.149 (0.854–1.545)

0.358

N

1.755 (1.432–2.151)

 < 0.001

0.998 (0.636–1.566)

0.994

M

1.718 (0.916–3.223)

0.091

0.311 (0.078–1.226)

0.095

Pathologic stage

1.660 (1.410–1.954)

 < 0.001

1.989 (1.183–3.346)

0.009

Smoking

0.910 (0.510–1.625)

0.752

1.501 (0.713–3.159)

0.284

risk score

2.718 (1.957–3.776)

 < 0.001

2.315 (1.513–3.541)

 < 0.001

GSE68465 (overall survival)

Age

1.546 (1.194–2.001)

 < 0.001

1.723 (1.270–2.338)

 < 0.001

Gender

1.390 (1.073–1.801)

0.012

1.066 (0.782–1.453)

0.685

T

1.672 (1.394–2.007)

 < 0.001

1.467 (1.149–1.874)

0.002

N

2.012 (1.712–2.365)

 < 0.001

2.037 (1.688–2.458)

 < 0.001

Smoking

1.246 (0.790–1.965)

0.344

1.475 (0.908–2.397)

0.116

Risk score

3.553 (1.783–7.080)

 < 0.001

2.651 (1.264–5.560)

0.010

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