Figure 6
From: Baicalin target protein, Annexin A2, is a target of new antitumor drugs
(a, b) The structure of ANXA2 is colored in rainbow and baicalin is shown in grey. (a) Is a front view and (b) is a side view. (c, d) In the full-length ANXA2-baicalin binding model, the N-terminal domain of ANXA2 is shown in red, the C-terminal core domain is shown in blue, and baicalin is shown in yellow. ANXA2 is shown in cyan and baicalin in beige in the ΔN_ANXA2-baicalin binding model. Chloride ions are shown in green spheres. (e) Details of the baicalin-binding site of ANXA2 are shown with N-terminal domain residues in red and C-terminal core domain residues in blue. Hydrogen bonds are indicated by yellow dashed lines.
