Table 3 Bronchoscopic examination characteristics of patients with MDR/RR/pre-XDR-TBTB using bedaquiline or delamanid or none.
Characteristics, N (%) | Total (n = 101) | Bedaquiline (n = 32) | Delamanid (n = 25) | Non-bedaquiline or delamanid (n = 44) | χ2 | P value |
|---|---|---|---|---|---|---|
Subtypes of TBTB | 0.535a | 0.765 | ||||
Inflammatory infiltration | 29 (28.7) | 8 (25.0) | 9 (36.0) | 12 (27.3) | ||
Ulceration necrosis | 33 (32.7) | 13 (40.6) | 6 (24.0) | 14 (31.8) | ||
Granulation hyperplasia | 15(14.9) | 3 (9.4) | 6 (24.0) | 6 (13.6) | ||
Cicatrices stricture | 24 (23.8) | 8 (25.0) | 4 (16.0) | 12 (27.3) | ||
Tracheobronchial malacia | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
Lymph fistula | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
Site of lesions | ||||||
Trachea | 16 (15.8) | 5 (15.6) | 3 (12.0) | 8 (18.2) | 0.440b | 0.939 |
Right main bronchus | 18 (17.8) | 6 (18.8) | 4 (16.0) | 8 (18.2) | 0.134b | > 0.999 |
Right upper lobe bronchus | 44 (43.6) | 13 (40.6) | 10 (40.0) | 21 (47.7) | 0.552 | 0.759 |
Right middle bronchus | 12 (11.9) | 3 (9.4) | 1 (4.0) | 8 (18.2) | 2.971b | 0.196 |
Right middle lobe bronchus | 8 (7.9) | 1 (3.1) | 1 (4.0) | 6 (13.6) | 2.862b | 0.285 |
Right lower lobe bronchus | 15 (14.9) | 3 (9.4) | 6 (24.0) | 6 (13.6) | 2.348b | 0.304 |
Left main bronchus | 30 (29.7) | 10 (31.3) | 8 (32.0) | 12 (27.3) | 0.224 | 0.894 |
Left upper lobe bronchus | 43 (42.6) | 17 (53.1) | 13 (52.0) | 13 (29.5) | 5.420 | 0.067 |
Left lower lobe bronchus | 22 (21.8) | 7 (21.9) | 5 (20.0) | 10 (22.7) | 0.070 | > 0.999 |
Number of lesions involved | 1.011 | 0.603 | ||||
Single | 48 (47.5) | 13 (40.6) | 12 (48.0) | 23 (52.3) | ||
Multiple | 53 (52.5) | 19 (59.4) | 13 (52.0) | 21 (47.7) | ||
Tracheobronchial stenosis | 75 (74.3) | 20 (62.5) | 18 (72.0) | 37 (84.1) | 0.556a | 0.757 |
Mild | 35 (34.7) | 9 (28.1) | 9 (36.0) | 17 (38.6) | ||
Moderate | 11 (10.9) | 2 (6.3) | 4 (16.0) | 5 (11.4) | ||
Severe | 29 (28.7) | 9 (28.1) | 5 (20.0) | 15 (34.1) | ||
Tracheobronchial obstruction | 15 (14.9) | 6 (18.8) | 3 (12.0) | 6 (13.6) | 0.620b | 0.821 |
