Table 3 Unique, dynamic, universal, and random mutations in the spike protein of JN.1 as compared to the BA.2 sequence.
Unique mutation | Dynamic mutation | Universal mutation | Random mutation | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NTD | RBD | SD | HR1/HR2 | NTD | RBD | SD | NTD | RBD | SD | NTD | RBD | SD | FP | HR1/HR2 |
V83F | T33R | – | – | P85K | – | – | – | – | – | R21T | I332V | E554K | H681R | S939F |
L84K | F456L | – | – | V90Y | – | – | – | – | – | A27S | G339H | A570V | – | P1143L |
P85L | Q506P | – | – | – | – | – | – | – | – | S50L | R346T | P621S | – | |
F86L | P507T | – | – | – | – | – | – | – | – | V127F | K356T | – | – | – |
N87I | – | – | – | – | – | – | – | – | – | F157S | S375F | – | – | – |
D88V | – | – | – | – | – | – | – | – | – | R158G | T376A | – | – | – |
V90L | – | – | – | – | – | – | – | – | – | L212I | R403K | – | – | – |
Q218L | – | – | – | – | – | – | – | – | – | L216F | V445H | – | – | – |
Y170E | – | – | – | – | – | – | – | – | – | H245N | G446S | – | – | – |
T307Q | – | – | – | – | – | – | – | – | – | A264D | N450D | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | L452W | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | L455W | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | N460K | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | N481K | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | A484K | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | F486P | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | R493Q | – | – | – |
– | – | – | – | – | – | – | – | – | – | – | H505Y | – | – | – |
