Table 7 The binding energies of the interaction of wild-type and mutated structures with different receptors in the molecular docking investigation.
Mutations (RBD) | Docking score (ACE2) | Docking score (CD147) | Docking score (CD209L) | Mutations (NTD) | Docking score (AXL) |
|---|---|---|---|---|---|
Wild | − 998.7 | − 922 | − 1170.3 | Wild | − 848.1 |
I332V | 997.3 | − 910.7 | − 1171.4 | R21T | − 718.2 |
K356T | − 992.2 | − 932.9 | − 1175.7 | S50L | − 740.0 |
N450D | − 997.9 | − 942.5 | − 1172.4 | V127F | − 737.5 |
L455S | − 995 | − 940.9 | − 1171.5 | F157S | − 720.0 |
N481K | − 1011.9 | − 928.9 | − 1183.7 | R158G | − 716.5 |
R403K | − 996.4 | − 945 | − 1183.9 | L216F | − 741.8 |
All | − 959.2 | − 951.2 | − 1177.7 | H245N | − 726.0 |
A264D | − 740.5 | ||||
All | − 702.1 |
