Table 3 Associations (β with 95% confidence intervals) between log transformed values in serum biomarkers and severity of hand-arm vibration injury, estimated by Generalized Linear Models in 92 patients with hand-arm vibration injury. Statistically significant associations in bold face.
Biomarker | Raynaud’s phenomenon (Griffin score) n = 82 | Vibration perception threshold (sensibility index) n = 92 | ||
---|---|---|---|---|
Crude | Adjusted | Crude | Adjusted | |
ICAM-1 | − 0.00 (− 0.01 to 0.00) | − 0.00 (− 0.13 to 0.14) | ||
MCP-1 | − 0.01 (− 0.02 to 0.00) | − 0.01 (− 0.02 to 0.00)a | − 0.21 (− 0.60 to 0.18) | − 0.25 (− 0.64 to 0.14)a |
TM | 0.01 (0.00–0.03) | − 0.26 (− 0.76 to 0.23) | ||
vWf | 0.01 (0.00–0.02) | 0.01 (0.00–0.02)b | − 0.06 (− 0.37–0.26) | |
Without concurrent diseases | − 0.23 (− 0.55 to 0.08)c | |||
With concurrent diseases | 0.59 (− 0.07 to 1.3)c | |||
HSP27 | 0.01 (− 0.00–0.02) | 0.01(− 0.01 to 0.02)d | − 0.04 (− 0.52 to 0.43) | − 0.01 (− 0.45 to 0.46d |
Caspase-3 | 0.03 (0.00–0.05) | 0.03 (0.01–0.05)e | − 0.44 (− 1.3 to 0.47) | |
Without concurrent diseases | − 1.1 (− 2.1 to 0.09) | |||
With concurrent disease | 1.4 (0.28–3.1) |