Figure 3
From: New insights into the pro-oxidant mechanism of dehydroleucodine on Trypanosoma cruzi
The reducing agent gluthatione (GSH) protects T. cruzi epimastigotes from DhL and DC-X6 antiproliferative activity. Parasites were incubated with different concentrations of compounds, in the absence or in the presence of 3 mM GSH for 24 h or 48 h. After incubation aliquots were collected and the parasites were counted. Bars represent the means ± SEM of parasite concentration from three independent experiments. (**) (***) and (****) indicate significant differences from the controls (p < 0.002, p < 0.01 and p < 0.001 respectively). GSH alone was also used as control. (A) 24 h, (B) 48 h of DhL. (C) 24 and 48 h of DC-X6.
