Table 1 Hemodynamic parameters and heart rate values after administration of atropine and propranolol in spontaneously hypertensive rats (SHR) Untrained (N = 16) and Trained (N = 16) treated with vehicle (N = 08) or pyridostigmine bromide (PYR; N = 08).

Hemodynamic parameters

 Systolic Blood Pressure, mmHg

188 ± 6

167 ± 3^a

159 ± 6^a

158 ± 5^a,b

F_(1,31):4.59

0.041

F_(1,31):14.97

< 0.001

F_(1,31):4.08

0.053

 Diastolic Blood Pressure, mmHg

146 ± 8

127 ± 3^a

127 ± 7^a

119 ± 4^a

F_(1,31):4.64

0.040

F_(1,31):5.08

0.032

F_(1,31):0.86

0.36

 Mean Blood Pressure, mmHg

163 ± 7

143 ± 3^a

140 ± 6^a

135 ± 4^a

F_(1,31):5.34

0.028

F_(1,31):9.22

0.005

F_(1,31):1.99

0.168

Tonic autonomic control

 Heart Rate, bpm

382 ± 5

351 ± 5^a

333 ± 4^a,b

315 ± 6^a,b,c

F_(1,31):24.81

< 0.001

F_(1,31):73.03

< 0.001

F_(1,31):1.24

0.208

 HR atropine, bpm

408 ± 5

390 ± 3^a

372 ± 3^a,b

366 ± 5^a,b

F_(1,31):8.74

0.006

F_(1,31):53.95

< 0.001

F_(1,31):2.42

0.131

 Δ HR atropine, bpm

26 ± 5

39 ± 4^a

39 ± 3^a

52 ± 6^a,b,c

F_(1,31):7.60

0.010

F_(1,31):7.61

0.010

F_(1,31):0.07

0.979

 HR propranolol, bpm

306 ± 5

295 ± 6

300 ± 6

283 ± 4^a,c

F_(1,31):7.02

0.013

F_(1,31):2.65

0.115

F_(1,31):0.42

0.52

 Δ HR propranolol, bpm

76 ± 5

56 ± 5^a

33 ± 5^a,b

32 ± 6^a,b

F_(1,31):4.03

0.054

F_(1,31):42.06

< 0.001

F_(1,31):3.66

0.066

 IHR, bpm

328 ± 4

306 ± 4^a

319 ± 3^b

294 ± 3^a,b,c

F_(1,31):39.14

< 0.001

F_(1,31):7.19

0.012

F_(1,31):0.19

0.67