Figure 3
From: High fat diet affects the hippocampal expression of miRNAs targeting brain plasticity-related genes
HFD inhibits the expression of synaptic and non-synaptic proteins targeted by upregulated miRNAs. (A) Immunoblots and bar graphs showing the expression of SYT1, CAMK1D, GRIN2B, GRIN2A, SNAP25, and SEPTIN3 in the hippocampi of SD and HFD mice (n = 6 per group; statistics by unpaired Student’s t-test). B) Immunoblots and bar graphs showing the expression of CPEB1, NOVA1, SATB2, FOXP2, and CREB in the hippocampi of SD and HFD mice. (n = 6 per group; statistics by unpaired Student’s t-test). Original blots/gels are presented in Supplementary Fig. 1. Data are expressed as mean ± SEM. *p < 0.05; n.s. not significant.
