Figure 1 | Scientific Reports

Figure 1

From: Comprehensive analysis identifies ubiquitin ligase FBXO42 as a tumor-promoting factor in neuroblastoma

Figure 1

Discovery of ubiquitination-related differential proteins and aberrant pathways in N-Myc amplified neuroblastoma. (A) Volcano plot of differentially expressed proteins in the proteomic dataset of 34 cases. The x-axis represents the fold change in gene expression, and the y-axis represents FDR. Red and blue dots indicate significantly upregulated and downregulated genes, respectively. (B) Venn diagram of differentially expressed proteins, E3 ubiquitin ligases, and deubiquitinases. (C,D) Gene Ontology (GO) analysis of 610 differentially expressed proteins, including biological process, cellular component, and molecular function. (F) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of the 610 differentially expressed proteins.

Back to article page