Figure 2
Development of the ubiquitination gene prognostic model. (A) Lasso coefficient plot of 28 prognostic-related ubiquitination genes in the Discovery (GSE62564 microarray) dataset. Grey represents eliminated genes. (B) Partial likelihood deviance of variables revealed by Lasso regression. Red dots indicate partial likelihood deviance values, grey lines represent standard errors (SE), and left and right vertical dashed lines represent the minimum standard with 1-SE standard and optimal values. (C,D) Distribution of risk scores (C) and survival status of patients (D) for the 13-gene prognostic model. (E) Kaplan–Meier analysis of the 13-gene risk score. (F) Heatmap showing the expression of the 13 feature genes (R 4.0.2, R package “pheatmap”). (G) ROC curve analysis of the 13-gene risk score.
