Figure 6 | Scientific Reports

Figure 6

From: Comprehensive analysis identifies ubiquitin ligase FBXO42 as a tumor-promoting factor in neuroblastoma

Figure 6

Comprehensive analysis of the role of E3 ubiquitin ligase FBXO42 in neuroblastoma. (A) Predicted protein structure of FBXO42 by alpha fold. (B) Analysis of genetic mutations of FBXO42 in neuroblastoma cohort. (C) Immunofluorescence localization analysis of FBXO42 (green) in A-431, U2OS, and U251 cells. (D) Immunohistochemistry analysis of FBXO42 expression levels in normal human adrenal glands; HPA025071-1 and HPA025071-2 are image IDs in the HPA database. (EH) Gene expression levels of FBXO42 in different clinical-pathological parameter group samples, including COG risk stratification (E), N-Myc amplification status (F), gender (G), and INSS stage (H). (I) Protein–protein interaction network of FBXO42. (J,K) 11 protein KEGG pathways (J) and GO term enrichment (K) included in the interaction network.

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