Figure 10 | Scientific Reports

Figure 10

From: Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model

Figure 10

(A) TEM image of CQD (Scale bar = 10 nm), (B) SEM image of P-CQD NPs (Scale bar = 100 nm), (C) in vitro release profile of CQD from P-CQD NPs data = mean ± SD, n = 5, (D) emission spectra of CQD, (E) schematic image of P-CQD NPs, (F) fluorescent bio tracking of P-CQD NPs 1, 6, 24, and 48 h after IV injection, (G) fluorescent intensity of dissected organs after 48h, (H) fluorescent intensity of injected sample (before injection), (I) average signal count emitted from each organ, (Data = mean ± SD) and (J) percent of signal count in organs, (Data = mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).

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