Figure 7 | Scientific Reports

Figure 7

From: Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model

Figure 7

(A) Apoptosis rate (TUNEL assay) of the control (tumor-bearing rats), P-PTX NPs, and P-MTX NPs + P-PTX NPs, (scale bar = 20 µm, The scale bars are the same in all pictures), (B) NF-ĸB expression of the control P-PTX NPs and P-MTX NPs + P-PTX NPs treated rat brain (scale bar = 20 µm, The scale bars are the same in all pictures), (C) quantitative analysis of TUNEL, and (D) quantitative analysis of NF-ĸB, (Data = mean ± SD, *P < 0.05, ** P < 0.01, ***P < 0.001, ****P < 0.0001).

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